What İs Lutetium ?

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Lutetium-177 (Lu-177) is a radioactive isotope used for medical purposes and plays an important role especially in cancer treatment. Here is basic information about Lu-177:


1. Physical Properties

Atomic Number: 71

Half-Life: 6.65 days

Radiation Type: It emits beta and gamma radiation. This combination allows it to be used both to destroy cancer cells during treatment and for medical imaging.



2. Medical Use

Lutetium-177 is used in the treatment of certain types of cancer, such as neuroendocrine tumors and prostate cancer. The treatment method is called radioactive molecule therapy and provides targeted radiotherapy.


PRRT (Peptide Radioreceptor Therapy): Lu-177 is injected into the patient's body by binding to a biomolecule. This biomolecule targets receptors specific to cancer cells, so Lu-177 is directed towards the tumor. The radioactive spread destroys cancer cells while causing minimal damage to surrounding tissues.

3. Prostate Cancer Treatment

Lu-177 is used in prostate cancer treatment by targeting PSMA (Prostate Specific Membrane Antigen). PSMA is found at high levels in prostate cancer cells. Lu-177 is combined with a molecule that binds to PSMA and is directed to these cells and destroys the cancer cells.


4. Advantages

Targeted Therapy: Lu-177 is delivered to the body through molecules that specifically bind to cancer cells. This causes more specific damage to cancer cells with fewer side effects compared to other treatments.


Combination of Treatment and Imaging: Since it emits both beta and gamma radiation, tumor size and location can also be monitored during treatment.


5. Side Effects

Although it has fewer side effects compared to other radiotherapy methods, some patients may experience side effects such as fatigue, nausea, and bone marrow suppression during Lu-177 treatment.


Lu-177 offers an effective and innovative solution in cancer treatment, helping to improve the quality of life, especially in advanced cancer cases.

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